Gentamicin Surgical Prophylaxis Dosing Guidelines

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• Prophylactic gentamicin dosing is based on patient height and approximates to 5mg/kg/ideal body weight, capped at 400mg.
• Doses of gentamicin can be given by slow IV injection over 3-5 minutes.
• Patients receiving aminoglycosides as a slow IV bolus should be closely monitored for other signs of extravasation or infiltration e.g. swelling, redness, coolness or blanching at the cannula insertion site.
• Avoid gentamicin if eGFR <20mls/min/1.73m2: seek advice on alternative from microbiology. In renal transplant patients avoid gentamicin and seek advice from microbiology or renal team.

Height ranges (cm)	Gentamicin Dose (mg)  Males	Gentamicin Dose (mg) Females
142 -146	240	200
147 -154	280	240
155-164	320	280
165-174	360	320
≥ 175	400	400