Venesection for Iron Overload, Paediatrics

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Iron overload can lead to multiple organ dysfunction/failure and poor quality of life in a variety of patients with different haematological conditions, including haemoglobinopathies, polycythaemias, haemochromatosis and post haematopoietic stem cell transplant. Patients entering into haematopoietic stem cell transplantation with iron overload have an increased risk of delayed engraftment, veno-oclusive disease (VOD), infection and GVHD. 

In addition to oral or parenteral iron chelation, venesections may also be used as a treatment modality for the management of iron overload in selected patients. This SOP aims to define indications and contra-indications for the use of venesections in this clinical scenario, the competencies and equipment required, and to describe the procedures to be followed.

NOTE: this guideline is hosted on the NHSGGC Paediatrics Guidelines website. Clicking on the link below will open the guideline in a new window.


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